ChemicalBook > CAS DataBase List > AC-DEVD-CHO

AC-DEVD-CHO

Product Name
AC-DEVD-CHO
CAS No.
169332-60-9
Chemical Name
AC-DEVD-CHO
Synonyms
MF 191;AC-DEVD-CHO;AC-DEVD-ALDEHYDE;AC-DEVD-CHO?, >98%;CASPASE-3 INHIBITOR;ACETYL-DEVD-ALDEHYDE;Ac-Asp-Glu-Val-Asp-H;CASPASE-3 INHIBITOR I;AC-DEVD-CHO USP/EP/BP;AcDEVDCHO,Ac DEVD CHO
CBNumber
CB6488321
Molecular Formula
C20H30N4O11
Formula Weight
502.47
MOL File
169332-60-9.mol
More
Less

AC-DEVD-CHO Property

Boiling point:
1021.1±65.0 °C(Predicted)
Density 
1.374±0.06 g/cm3(Predicted)
RTECS 
EK7643000
storage temp. 
-20°C
solubility 
H2O: 1 mg/mL
form 
powder
pka
4.19±0.10(Predicted)
color 
white
Sensitive 
Moisture Sensitive
More
Less

Safety

WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
235420
Product name
Caspase-3 Inhibitor I
Packaging
1mg
Price
$113
Updated
2024/03/01
Sigma-Aldrich
Product number
235420
Product name
Caspase-3 Inhibitor I
Packaging
5mg
Price
$475
Updated
2024/03/01
Alfa Aesar
Product number
J65204
Product name
N-Acetyl-Asp-Glu-Val-Asp-al
Packaging
5mg
Price
$401
Updated
2023/06/20
Alfa Aesar
Product number
J65204
Product name
N-Acetyl-Asp-Glu-Val-Asp-al
Packaging
1mg
Price
$101
Updated
2021/12/16
Sigma-Aldrich
Product number
A0835
Product name
N-Acetyl-Asp-Glu-Val-Asp-al
Purity
≥95%, powder
Packaging
1mg
Price
$161
Updated
2024/03/01
More
Less

AC-DEVD-CHO Chemical Properties,Usage,Production

Uses

Reversible inhibitor of interleukin-1beta converting enzyme (ICE); also inhibits caspase-3 cleavage of poly(ADP-ribose) polymerase

Uses

N-Acetyl-Asp-Glu-Val-Asp-al has been used as a caspase inhibitor in muscle samples, smooth muscle cells and Jurkat T-cells.

Definition

ChEBI: A tetrapeptide consisting of two L-aspartic acid residues, an L-glutamyl residue and an L-valine residue with an acetyl group at the N-terminal and with the C-terminal carboxy group reduced to an aldehyde. It is an inhibitor of caspase-3/7.

General Description

N-Acetyl-Asp-Glu-Val-Asp-al (Ac-DEVD-CHO) is a tetrapeptide with N-terminal acetylation and C-terminal aldehyde conjugation.

Biochem/physiol Actions

N-Acetyl-Asp-Glu-Val-Asp-al (Ac-DEVD-CHO) aids in the recovery of stunned myocardium by its caspase inhibition functionality.

AC-DEVD-CHO Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

AC-DEVD-CHO Suppliers

China 55 India 1 Switzerland 1 United Kingdom 2 United States 14 Global 73
VDM Biochemicals
Tel
0330-2528181
Fax
0330-2528171
Email
sales@vdmbio.com
Country
United States
ProdList
510
Advantage
64
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4863
Advantage
58
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9926
Advantage
65
Alabiotech Inc.
Tel
001-619-354-5251
Fax
001-855-855-6087
Email
sales@alabiotech-e.com
Country
United States
ProdList
972
Advantage
60
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6393
Advantage
58
Aladdin Scientific
Tel
+1-833-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57511
Advantage
58

169332-60-9, AC-DEVD-CHORelated Search:

AC-IETD-CHO N-acetyl aspartyl-glutaMic acid AC-DEVD-CHO BIOTIN-ASP(OME)-GLU(OME)-VAL-ASP(OME)-FLUOROMETHYLKETONE AC-DEVD-AMC ORCOKININ AC-DEVD-AFC AC-DEVD-CHO BIOTIN-DEVD-CHO MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP)-OH AC-DEVD-PNA CYCLIC ADIPOYL-(6-AMINO)HEXANOYL-DEVD-RHODAMINE 110, TRIETHYLAMINE SALT BIOTIN-X-DEVD-FMK (7-METHOXYCOUMARIN-4-YL)ACETYL-L-ASPARTYL-L-GLUTAMYL-L-VALYL-L-ASPARTYL-L-ALANYL-L-PROLYL-N-EPSILON-(2,4-DINITROPHENYL)-L-LYSINE AMIDE AC-ASP-GLU-VAL-ASP-BETA-NA BIOTINYL-ASP(OME)-GLU(OME)-VAL-ASP(OME)-FLUOROMETHYLKETONE ANTI-IP3 RECEPTOR TYPE I NEUTRALIZING PEPTIDE AC-ASP-GLU-VAL-ASP-CHO TFA

  • Ac-DEVD-CHO,N-Acetyl-Asp-Glu-Val-Asp-al, >98%
  • AC-DEVD-CHO?, >98%
  • Caspase-3 Inhibitor I - CAS 169332-60-9 - Calbiochem
  • N-ACETYL-L-ALPHA-ASPARTYL-L-ALPHA-GLUTAMYL-N-(2-CARBOXY-1-FORMYLETHYL)-L VALINAMIDE
  • N-AC-ASP-GLU-VAL-ASP-CHO
  • N-ACETYL-ASP-GLU-VAL-ASP-AL
  • N-ACETYL-ASP-GLU-VAL-ASP-CHO (ALDEHYDE)
  • CPP32/APOPAIN INHIBITOR
  • CASPASE-3 INHIBITOR I
  • CASPASE-3 INHIBITOR (ALDEHYDE)
  • ACETYL-DEVD-ALDEHYDE
  • ACETYL-L-ASPARTYL-L-GLUTAMYL-L-VALYL-L-ASPART-1-AL
  • ACETYL-ASP-GLU-VAL-ASP-ALDEHYDE
  • AC-DEVD-CHO
  • AC-DEVD-ALDEHYDE
  • AC-ASP-GLU-VAL-ASP-ALDEHYDE
  • AC-ASP-GLU-VAL-ASP-ALDEHYDE (PSEUDO ACID)
  • AC-ASP-GLU-VAL-ASP-H (ALDEHYDE)
  • AC-ASP-GLU-VAL-ASP-CHO
  • Acetyl-aspartyl-glutamyl-valyl-aspartal
  • CASPASE-3 INHIBITOR
  • CASPASE 3 (APOPAIN) INHIBITOR 1
  • MF 191
  • N-acetyl-Asp-Glu-Val-Asp-Ala
  • (4S,7S,10S,13S)-7-(2-carboxyethyl)-4-(carboxyMethyl)-13-forMyl-10-isopropyl-2,5,8,11-tetraoxo-3,6,9,12-tetraazapentadecan-15-oic acid
  • Ac-Asp-Glu-Val-Asp-H
  • CASPASE-3 INHIBITOR I;N-AC-ASP-GLU-VAL-ASP-CHO;ACETYL-ASPARTYL-GLUTAMYL-VALYL-ASPARTAL
  • L-Valinamide, N-acetyl-L-α-aspartyl-L-α-glutamyl-N-[(1S)-2-carboxy-1-formylethyl]-
  • N-Acetyl-Asp-Glu-Val-Asp-al >=95%, powder
  • AC-DEVD-CHO USP/EP/BP
  • Ac-DEVD-CHO，N-Acetyl-Asp-Glu-Val-Asp-al
  • Caspase 3 Inhibitor I,Caspase3 Inhibitor I
  • AcDEVDCHO,Ac DEVD CHO
  • 169332-60-9
  • Caspase 10
  • Caspases
  • Cell Biology
  • Cell Signaling and Neuroscience
  • Apoptosis and Cell Cycle
  • BioChemical
  • Inhibitors
  • peptides
  • Caspase 10
  • Caspase 3
  • Caspase 7
  • Caspase 8
  • Caspase Inhibitors
  • Caspase Inhibitors and Substrates
  • Peptides and Proteins
  • Peptides for Cell Biology
  • Protease Inhibitor Specificity Index
  • Protease Inhibitors
  • A to C
  • A-AM
  • Aldehydes
  • and Substrates
  • Apoptosis and Cell Cycle
  • Apoptosis Enzymes